Data integration for functional annotation

The team is involved in several integrative projects merging biological resources, bioinformatics predictions and statistical analyses. Databases and graphical users interfaces are relevant approaches to organize and visualize data integration efforts.

For several years now, we develop and maintain two databases FLAGdb⁺⁺ and CATdb  which help to improve insight in the biological roles of plant genes and give us an ideal medium to release the results of our projects to a broader community.

• FLAGdb⁺⁺ is a database on the structural and functional annotations of 6 plant genomes

• CATdb is a database dedicated to data generated by the transcriptomic platform of IPS2.

The module GEM2Net of CATdb presents a large co-expression study of 18 stress categories. Functions were associated with computed clusters by integrating various resources (GO, sub-cellular localization of proteins, Hormone Families, Transcription Factor Families and a refined stress-related gene list associated to publications) and gene networks were displayed by exploiting protein–protein and transcription factors-targets interactions.

Besides, we are involved in several integrative projects merging biological resources, bioinformatics predictions and statistical analyses.